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    HEAD-TO-HEAD COMPARISON

    Focusrite Scarlett 2i2 4th Gen vs PreSonus AudioBox USB 96

    We compare the Focusrite Scarlett 2i2 4th Gen and PreSonus AudioBox USB 96 head-to-head on performance, features, value, and more. Here's which one wins.

    Our Pick

    Focusrite Scarlett 2i2 4th Gen

    Scored 9.5/10 in our testing

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    Best Overall

    Focusrite Scarlett 2i2 4th Gen

    2-in/2-out with Air mode and auto-gain at 192kHz

    Overall:9.5/10Winner
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    Best Budget

    PreSonus AudioBox USB 96

    2-in/2-out with Studio One Artist included under $100

    Overall:9.2/10
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    Score Breakdown

    Focusrite Scarlett 2i2 4th GenCategoryPreSonus AudioBox USB 96
    9.5/10 ✓Performance8.4/10
    8.4/10 Features8.4/10
    9.5/10 ✓Ease of Use9.1/10
    9.2/10 ✓Value8.8/10
    9.5/10 ✓Overall9.2/10

    Specs Comparison

    Focusrite Scarlett 2i2 4th GenSpecPreSonus AudioBox USB 96
    See Amazon for full specsDetailsSee Amazon for full specs

    Focusrite Scarlett 2i2 4th Gen

    Pros

    • + Low-latency performance response
    • + Velocity-sensitive keys and pads
    • + Compact portable design

    Cons

    • − Software bundle may be lite version

    PreSonus AudioBox USB 96

    Pros

    • + USB bus-powered no adapter needed
    • + High-quality audio preamps
    • + Integrates deeply with DAW

    Cons

    • − Limited onboard controls

    Our Verdict

    Based on our scoring, the Focusrite Scarlett 2i2 4th Gen comes out on top with an overall score of 9.5/10. 2-in/2-out with Air mode and auto-gain at 192kHz.

    Buy the Focusrite Scarlett 2i2 4th Gen on Amazon

    Read the full Best Audio Interfaces 2026 guide for complete reviews of all 5 products.

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